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In the skin of the fruit, there is a large amount of a natural substance called Hydroxycitric Acid (HCA). This is the active ingredient in Garcinia Cambogia extract… that is, the substance that produces the weight loss effects. Bottom Line: Garcinia Cambogia is a plant often used in Asian recipes.

The skin of the fruit contains a substance called Hydroxycitric Acid (HCA), which is the active ingredient.

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In the skin of the fruit, there is a large amount of a natural substance called Hydroxycitric Acid (HCA). This is the active ingredient in Garcinia Cambogia extract… that is, the substance that produces the weight loss effects.

Bottom Line: Garcinia Cambogia is a plant often used in Asian recipes. The skin of the fruit contains a substance called Hydroxycitric Acid (HCA), which is the active ingredient. Does Garcinia Cambogia Actually Work.

Woman Smiling and Holding a Supplement I managed to find several research studies on Garcinia Cambogia, in both animals and humans. According to some studies in rats, it can inhibit a fat producing enzyme called Citrate Lyase, making it more difficult for the body to produce fat out of carbohydrates (1).

Other rat studies show increased levels of the neurotransmitter serotonin. This could theoretically Hamhurger to reduced appetite and cravings (2).

There are actually a whole bunch of studies in rats showing that Garcinia Cambogia consistently leads to significant weight loss (3, 4, 5, 6). However, what works in rats doesnt always work in humans. Bottom Line: Studies in rats show that the active ingredient in Garcinia Cambogia can inhibit a fat producing enzyme called Citrate Lyase and increase serotonin levels, leading to significant weight loss.

A Look at Some Human Studies Fortunately, I also found several human studies on Garcinia Cambogia. All of these studies are so-called randomized controlled trials, which are the gold standard of scientific experiments in humans.

The biggest of the studies included 135 overweight individuals, which were split into two groups (7): Treatment group: 1 gram of Garcinia Cambogia Extract, 3 times per day, taken 30 minutes before meals. Placebo group: The other group took dummy pills (placebo). Patyt groups also went on a high-fiber, low calorie diet.

These were the results of the 12 week study, which was published in The Journal of The American Medical Association (a highly respected scientific journal): Heymsfield, et al. 1998 As Hamburger single patty can see, both groups lost weight.

But the group taking Garcinia Cambogia extract actually lost less weight (3. 2 kg 7 pounds) pagty the placebo group (4. Hamburger single patty kg 9 pounds). The researchers also looked at body fat percentage. The placebo group lost 2. 16, while the group taking Garcinia Cambogia lost only 1. However, the difference was not statistically significant, meaning that paatty results could have been due to chance.

More Studies In another study with 89 overweight females, Garcinia Cambogia did lead to 1. 3 kg (2. 8 pounds) more weight loss compared to placebo, over a period of 12 weeks.

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It used to be an obscure hard-to-find ingredient, but recently the Internet has exploded with websites selling weight loss products based on an extract of Hamburgrr fruit sigle it even got some decidedly hucksterish treatment from Dr.

Oz, a TV personality made famous by Patyt Winfrey. The fruit is known in India as gambooge. It is apparently also an ingredient in some weight loss products as hydroxycitric acid. Oz promoted it and continues to assert that garcinia cambogia is an effective aid to weight loss. The claims for weight loss are nothing short of outlandish and there is real science that suggests the whole thing is a hoax.

Studies that claim to have found weight loss were carried out on animals. Studies involving humans are for the most part badly designed. A few quality studies have been carried out over the years, starting in 1998 with a double-blind, placebo-controlled trial of 135 adults over 12 weeks published in The Journal of the American Medical Association. They found no evidence that hydroxycitric acid, the active ingredient in weight loss products made from garcinia cambogia, produced significant weight loss.

The American Journal of Clinical Nutrition in 2004 published a systematic review of meta-analyses and clinical trials on dietary supplements for weight loss by complementary medicine researchers at the Universities of Exeter and Plymouth. None of the over-the-counter weight loss aids worked, including garcinia cambogia. Late in 2010 the peer-reviewed Journal of Obesity published a meta-analysis of studies testing the garcinia as a weight loss aid.

Of the 23 trials they identified, 12 were methodologically sound enough to include in their analysis. The analysis revealed that some statistically significant weight loss occurred, but the magnitude of the effect is small and the clinical relevance is uncertain. They also found that gastrointestinal adverse events were twice as likely in the hydroxycitric acid group as in the placebo group.

When you are considering the potential benefits of products look for meta-analysis studies that take in all the sound research available. One-off studies that get a significant result are not evidence of anything. Only when an HHamburger is repeated in many studies by many scientists should you believe.

RANDY SHOREs new cookbook Grow What You Eat, Eat What You Grow is now available at Chapters, Book Warehouse, Barbara-Jos Books to Cooks and Whole Foods. So, my Top Secret Garcinia experience was neither super impressive, nor super disappointing.

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